| Certain molecular structures have been associated with radical quenching activity. In polyphenol moieties, 3',4'- dihydroxy groups substituted in the B ring and conjugation between the A and B rings, e.g. quercetin, confers antioxidant capacity four times that of the standard vitamin E analogue, Trolox. 1 |
By way of contrast, the epicatechin structure which lacks the conjugation through the C ring but still has a (4',5'-) dihydroxy structure, has only 50% of the activity of quercetin.
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| Epicatechin |
| Similarly, kaempferol which lacks the dihydroxy structure in the B ring but still has conjugation through the A and B rings, also retains about 50% of the activity of quercetin. Both kaempferol and epicatechin still have more activity than vitamin C, and these theoretical observations agree, in the case of epicatechin, with the experimental data on apples. Go to >>>> Antioxidant potencies |
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| Kaempferol
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References 1. C.A. Rice-Evans et al., Free Radic. Res. (1995), (4) 375-383. Permission to reprint granted by Taylor and Francis. |
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